WWE SmackDown! Here Comes The Pain Roster
- A-Train
- Batista
- Big Show
- Booker T
- Brock Lesnar
- Bubba Ray Dudley
- Charlie Haas
- Chavo Guerrero
- Chris Benoit
- Chris Jericho
- Christian
- D-Von Dudley
- Eddie Guerrero
- Edge
- Eric Bischoff
- Goldberg
- Goldust
- The Hurricane
- Jazz
- John Cena
- Kane
- Kevin Nash
- Kurt Angle
- Lance Storm
- Lita
- Matt Hardy
- Randy Orton
- Rey Mysterio
- Rhyno
- Ric Flair
- Rico
- Rikishi
- Rob Van Dam
- The Rock
- Rodney Mack
- Sable
- Scott Steiner
- Sean O'Haire
- Shawn Michaels
- Shelton Benjamin
- Stacy Keibler
- Stephanie McMahon
- Steve Austin
- Steven Richards
- Tajiri
- Test
- Torrie Wilson
- Triple H
- Trish Stratus
- Ultimo Dragon
- Undertaker
- Val Venis
- Victoria
- Vince McMahon
Legends:
- Animal
- George Steele
- Hawk
- Hillbilly Jim
- Iron Sheik
- Jimmy Snuka
- Nikolai Volkoff
- Roddy Piper
- Sgt. Slaughter
- Ted Dibiase Sr.
- The Undertaker (Classic Attire)
Also, Jeff Hardy , Nunzio , John Stamboli , Hulk Hogan and Ultimate Warrior were supposed to be featured in HCTP, but were later removed. However, their select screen images are still on the disc.